Cisplatin has been used for many years in the treatment of mesothelioma. It has also been used for treating a number of other cancers as well. Cisplatin acts on the DNA of cancerous cells, making it difficult for these cells to duplicate their DNA. Cisplatin is usually used together with other drugs. It is administered intravenously (through the veins) or through a central line.

Some side effects of Cisplatin can be quite severe and may include some of the following:

  • A higher risk of infections
  • Fatigue
  • Problems with breathing/Tiredness/Weakness
  • Nausea and Vomiting
  • Bruising/Bleeding
  • Hair loss
  • Loss of hearing and ringing in the ears
  • Loss of appetite/Loss of taste/Metallic taste
  • Numbness or tingling in extremities (such as hands or feet)
  • Allergic reactions
  • Blurred vision
  • Kidney problems
  • Loss of fertility
  • Amenorrhea (Absence of menstrual periods)