The symptoms of pericardial mesothelioma are as follows:

  • Fluid accumulation around the heart
  • Chest pain (ranging from mild to severe)
  • Shortness of breath
  • Persistent coughing
  • Extreme fatigue (with little physical activity)
  • Heart palpitations


Fluid accumulates around the heart due to the growth of tumors in the pericardial region. Most of the symptoms of pericardial mesothelioma are attributed to the accumulation of this fluid since the accumulated fluid interferes with the function of the heart. Pericardial mesothelioma symptoms are often wrongly mistaken as an indication of some type of heart disease.